Unpleasant sequelae of benzodiazepine sedation
نویسندگان
چکیده
منابع مشابه
Between benzodiazepine over-sedation and neurological damage
1-OHMG is known to have sedative properties [2,3]. Although the method described (i.e. high-performance liquid chromatography coupled to mass spectrometric detection) might be highly specific and sensitive to detect and quantify the presence of the 1-OHMG, the presence of an active substance irrespective of its quantity can never be solely indicative of a given (patho-)physiological response. D...
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he benzodiazepines are the second group of drugs used by anesthetists that could truly be called "multipurpose," the first being the phenothiazines. The most popular of the latter, chlorpromazine, is known by the trade name Largactil in Europe, indicating the multiplicity of fields in which it can be used. While the phenothiazines were the more versatile of the two, they were also the more toxi...
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We have examined in eight male volunteers the effect of midazolam sedation on the relationship between timing of spontaneous ventilations and heart beat. On 2 study days, subjects received either midazolam 0.1 mg kg-1 or saline placebo while recordings were made of ECG and ventilatory impedance pneumography. We observed in all midazolam-treated subjects clear evidence of synchronous or non-sync...
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These results were all obtained by dental anesthesiologists in our clinic actually conducting conscious sedation while observing the patients' response and appearance. Consequently, the anesthesiologist's preferences and skill seem to influence the drugs chosen and the method of use. In reviewing these 300 cases, we found many in which the procedure was completed within 40 min, and effective se...
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OBJECTIVE To compare the efficacy of continuous intravenous sedation with midazolam alone vs. midazolam plus fentanyl ("co-sedation") during mechanical ventilation. DESIGN A randomized, prospective, controlled trial. SETTING A ten-bed medical intensive care unit at a university hospital. PATIENTS Thirty patients with respiratory failure who were expected to require >48 hrs of mechanical v...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1990
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.1990.tb14749.x